Improving surgery recovery for children undergoing surgery for inflammatory bowel disease: Laying the groundwork

Principal Investigator: Mehul V. Rahul, MD; Co-Principal Investigator: Salva N. Balbale, MS, Doctoral Candidate Enhanced Recovery Protocols (ERPs) are evidence-based interventions that utilize perioperative education and counseling provided through surgery and recovery to safe discharge. ERPs have been found to decrease hospital length of stay, in-hospital costs, and complications among a variety of adult surgical populations, including those undergoing abdominal and gastrointestinal tract surgery. As many as 17 percent of the 70,000 children with IBD in the United States need surgery within five years of diagnosis to manage their disease. ERPs offer an opportunity to enhance the care of these young patients, yet these strategies are currently lagging in the pediatric setting. This study will lay the groundwork and provide a baseline assessment of ERPs in 15 pediatric surgical practice sites across the country. The investigators will evaluate the effectiveness and impact of ERPs on outcomes, and use their findings in the development of an implementation...

A Clinical Trial of Standard Repair Versus a Novel Repair for Hiatal Hernia

Principal Investigator: Eric S. Hungness, MD Muscular weakness at the junction of the diaphragm and esophagus (hiatal hernia) is a common problem that may result in heartburn, difficulty swallowing, or anemia. Current surgical repair techniques have an unacceptably high hernia recurrence rate. A novel surgical material was developed at Northwestern University and has demonstrated promising results in animal and human studies. This project will investigate the efficacy of an innovative mesh suture in hiatal hernia repair, as compared to the current gold standard material. The principle outcome of interest will be measured by a non-invasive x-ray examination 6 months following surgery. The hope is that patients undergoing repair with the novel material will have...